Carag Tissue Oxygenation Monitoring System

The Carag Tissue Oxygenation Monitoring System (CTOM) is a new near-infrared spectroscopy (NIRS) device to accurately measure the oxygenation of the belly to prevent severe complication in preterm babies. It allows early detection of life-threatening health concerns.

CTOM baby CTOM baby

Preterm babies can be monitored with CTOM to detect

  • Necrotizing enterocolitis (NEC)
  • Compensated shock

Until now abdominal NIRS measurements usually show a high degree of variability and therefore are not clinically useful. The reason are absorbers such as faeces and meconium, which are not taken into consideration by current NIRS instruments and interfere with the measurement. There is no instrument available today that is designed to measure the oxygenation of the abdomen correctly.

CTOM will precisely, non-invasively and continuously monitor the oxygen saturation through the belly of preterm babies using near-infrared light. The CTOM algorithm will analyze the reflected light and compensate the impact of intestinal content on the NIRS signal for optimal results and accuracy.

The CTOM sensor was designed based on extensive studies that assessed the optical characteristics of preterm babies' bellies and their intestinal content.

  • Currently a study with 10 preterm infants is in progress with the goal to show the safety, comfort of the sensor and the accuracy of the measurement
CTOM sensor close-up

NEC prevention

  • NEC is the most common gastrointestinal emergency of preterm babies and a leading cause of morbidity and mortality in this population. Studies show lower StOreadings on the abdomen tied to NEC.
  • Consequently, abdominal StO2 monitoring is a promising tool to help recognizing NEC and may serve clinicians as an additional tool in the decision process on further treatment.

Compensated shock

  • Preterm infants often have unstable blood circulation. They are in so-called compensated shock - their vital organs receive enough oxygen, but peripheral and non-vital organs may already suffer from insufficient oxygenation.
  • Since traditional monitoring only focuses on the vital organs, critical deterioration of the babies' status is often detected too late when the baby is already going into shock.

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